TCI Laboratories is working with the University of Gdańsk, the project’s research partner, to develop an innovative formulation intended to support joint function.

The project is co-funded by the European Union through the European Regional Development Fund under the European Funds for Pomerania 2021–2027 programme, Measure 1.1 — Research and Innovation in Enterprises.

Total project costPLN 3,786,337.69
European Union contributionPLN 2,325,118.26

Objectives

Supporting joint function through a new delivery technology.

The project aims to develop an innovative food supplement intended to support joint function and the musculoskeletal system. The proposed formulation combines three functional ingredients: Boswellia serrata extract, Nigella sativa extract and the enzyme nattokinase.

The capsule-in-capsule technology is being developed to enable sequential release of the ingredients in the gastrointestinal tract. The research will assess the properties of the individual ingredients and their combinations, together with the quality, stability and performance of the resulting formulation.

Research and development

Planned activities

Physicochemical and technological research

This part of the project focuses on developing the formulation and manufacturing technology. Activities include assessing ingredient compatibility and stability, investigating release profiles, and developing analytical methods for quality control.

The analytical work covers the determination of key compounds in the plant extracts and the measurement of nattokinase activity.

Cell-based, microbiological and ecotoxicological studies

Laboratory studies will assess the biological activity, safety, bioavailability and environmental impact of the selected functional ingredients.

Cell-based experiments will investigate biological responses relevant to the intended application, including inflammatory processes, cartilage cell function and oxidative stress.

Formulation, prototype testing and commercialisation preparation

Development activities will include manufacturing process validation, preparation of pilot batches, continued stability testing and full validation of analytical methods.

The project will also produce the quality and regulatory documentation needed to support commercialisation and transfer of the technology to an industrial partner.

Recipients and results

Who will benefit?

The intended end users are primarily older adults and people seeking support for joint function and mobility.

The direct recipients of the research results will be pharmaceutical companies or distributors of health-related products interested in bringing the formulation to market. The planned commercialisation model involves licensing the technology with the relevant quality documentation, research findings and manufacturing know-how.

Expected results

The project will deliver a capsule-in-capsule formulation and manufacturing process, validated analytical methods, pilot batches, stability data and supporting technical and quality documentation, prepared for transfer into commercial practice.

Project details

Funding information

Beneficiary and project leaderTCI Bogdan Banecki
Project partnerUniversity of Gdańsk
Grant agreement numberFEPM.01.01-IP.03-0016/25-00
ProgrammeEuropean Funds for Pomerania 2021–2027
Measure1.1 — Research and Innovation in Enterprises
FundEuropean Regional Development Fund
Intermediate BodyAgencja Rozwoju Pomorza S.A. — Pomerania Development Agency
Total project costPLN 3,786,337.69
European Union contributionPLN 2,325,118.26
Scheduled completion31 May 2029

Co-funded by the European Union.
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